Sun: 10:00 - 17:00
NEXT GENERATION SEQUENCING, NGS
Analysis of embryo genome
THE PROBABILITY OF PREGNANCY WITH PGD NGS
STUDY OF CHROMOSOMES
The criterion for prescription – increased risk of chromosomal or genetic disease. The goal of PGS is to identify embryos without specific genetic pathology (genetic or chromosomal). As a result, the diagnosis significantly increases the chances of pregnancy, reduces the number of non-productive IVF cycles and preserves the health of the woman (due to the decrease in the volume of hormones taken).
Application of methods of advanced analysis of the genome provides a comprehensive prognosis of the implementation of the genetic status at all stages of ontogeny the embryo-fetus-child and is the basis for decision-making about embryo transfer in ART programs.
(UP TO 65% - GENERAL GROUP, 69% - SENIOR REPRODUCTIVE AGE)
Targeted analysis of individual chromosomes or genes – monogenic diseases.
Study of chromosomal abnormalities (number and structure of chromosomes)..
Complex combined analysis - exclusion of individual pathology and accidental disorders. For example, the analysis of translocation and estimation of the number of chromosomes in the analysis of single gene and chromosomes.
We carry out PGS of embryos and PGD not only for couples who want to get pregnant, but also for donors
Pre-implantation genetic testing can be used for different groups of patients:
THE MOST COMMON METHOD OF EMBRYO SELECTION IS BASED SOLELY ON THEIR MORPHOLOGY – THERE IS NO CORRELATION BETWEEN THE MORPHOLOGICAL AND CHROMOSOMAL STATUS OF THE EMBRYO
THE RISK OF CHROMOSOMAL ABNORMALITIES IS IN ALL EMBRYOS IN ALL FAMILIES - THE FREQUENCY OF CHROMOSOME ABNORMALITIES OF THE EMBRYO INCREASES WITH THE AGE OF THE MOTHER.
ART / IVF - taking into account the biological status of the embryo does not give:
IVF does not reduce the risks of chromosomal abnormalities and monogenic diseases.
IVF as a method of infertility treatment does not make it possible to increase the probability of having a healthy child.
ART / IVF is performed in groups of population, increased and high risks of offspring pathology.
For each embryo it was determined:
trisomy on one chromosome
single chromosome monosomy
mosaic forms of aneuploidies
multiple - mosaic and full of aneuploidies
no deviations were found (recommended for transfer)
Classical genetic analysis reveals the changed number of chromosomes and large structural disorders. It cannot be used for embryo cells.