Petrovsky prospect 2, building 3
St. Petersburg
Mon-Sat: 8:30 - 20:30
Sun: 10:00 - 17:00

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Inherited diseases carrier screening test

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NEXTGEN 21

Our mission is –
healthy baby In
your arms

18 GENES STUDIED

TEST’S SENSIVITY

99%

TEST’S SPECIFICITY

99%

Each of us may be physically healthy, but be a carrier of one (or several) hereditary diseases at the same time, without being aware of it. The danger arises when both parents have mutations in the same gene and pass them on to their child.

Children's health is the greatest value. It is possible to check one’s genetic status in advance and assess the risk of having seriously ill children through a comprehensive gene our clinic has developed: NextGen21. The analysis allows us to identify clinically significant variants in the genes associated with 18 hereditary diseases - the most common and severe ones, leading to early death or a significant deterioration in the quality of life.

Not only we offer the test to the patients: We have implemented NextGen21 testing as part of our egg and sperm donors’ evaluation.

NEXTGEN 21: GENE AND DISEASES

AR - autosomal recessive; AD - autosomal dominant.

Gene
Disease

Inheritance

CFTR
Cystic fibrosis

AR

PAH
Phenylketonuria

AR

SMN1
Spinal muscular atrophy

AR

SMN2DMPK
Myotonic dystrophy type I

AR

DMD
Duchenne muscular dystrophy

X-linked

HTT
Huntington's Disease

AD

F8
Hemophilia A

X-linked

HBB
Beta-thalassemia

АР

HBB
Sickle cell anemia

AR

APC
Familial Adenomatous Polyposis type I and II
AD
MUTYH
Familial Adenomatous Polyposis type I and II
AR
IDUA
Mucopolysaccharidosis type I

AR

PKD1
Autosomal dominant polycystic kidney disease type I and II

AD

PKD2 AD PMP22
disease Charcot-Marie-Tooth

AD

VHL
disease Von Hippel - Lindau

AD

ATP7B
Wilson's disease

AR

GBA
Gaucher disease

AR

HEXA
Tay - Sachs

AR

BRCA1/BRCA2
Hereditary breast cancer and ovarian I and II

AD

To whom NextGen recommened to?

To everyone who is planning a pregnancy. Especially:

  • In case of hereditary diseases in family history
  • In case of consanguine marriage
  • To members of specific ethnic groups
  • To egg and sperm donors participating in programs

Our clinic will help you to choose a donor of gametes with a known genetic status who has been examined using NextGen21 test

NextGen test - technology and capabilities

  • Based on highly efficient NGS sequencing technology
  • High analytical characteristics (Sensitivity - 99%, specificity - 99%)
  • Allows to determine the status of the studied genes with a high degree of accuracy
  • Rules out carrier status of the most frequent and severe hereditary diseases

NextGen21 test significantly reduces the likelihood of hereditary diseases in children. Based on the test result, our geneticist calculates the risks and develops recommendations for each individual family.

NextGen 21 Inherited diseases carrier screening test386 €
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Petrovsky prospect, 2, building 3
Sportivnaya station

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