Inherited diseases carrier
screening test
NEXTGEN 21
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Our mission is –
healthy baby in Your arms
18 GENES STUDIED
TEST’S SENSITIVITY
TEST’S SPECIFICITY
Each of us may be physically healthy, but be a carrier of one (or several) hereditary diseases at the same time, without being aware of it. The danger arises when both parents have mutations in the same gene and pass them on to their child.
Children's health is the greatest value. It is possible to check one’s genetic status in advance and assess the risk of having seriously ill children through a comprehensive gene our clinic has developed: NextGen21. The analysis allows us to identify clinically significant variants in the genes associated with 18 hereditary diseases - the most common and severe ones, leading to early death or a significant deterioration in the quality of life.
Not only we offer the test to the patients: We have implemented NextGen21 testing as part of our egg and sperm donors’ evaluation.
NEXTGEN 21: GENE AND DISEASES
| Gene | Disease | Inheritance |
|---|---|---|
CFTR | Cystic fibrosis | AR |
PAH | Phenylketonuria | AR |
SMN1 | Spinal muscular atrophy | AR |
SMN2DMPK | Myotonic dystrophy type I | AR |
DMD | Duchenne muscular dystrophy | X-linked |
HTT | Huntington's Disease
| AD |
F8 | Hemophilia A | X-linked |
HBB | Beta-thalassemia
| АР |
HBB | Sickle cell anemia
| AR |
APC | Familial Adenomatous Polyposis type I and II | AD |
MUTYH | Familial Adenomatous Polyposis type I and II | AR |
IDUA | Mucopolysaccharidosis type I | AR |
PKD1 | Autosomal dominant polycystic kidney disease type I and II | AD |
PKD2 AD PMP22 | disease Charcot-Marie-Tooth | AD |
VHL | disease Von Hippel - Lindau | AD |
ATP7B | Wilson's disease | AR |
GBA | Gaucher disease | AR |
HEXA | Tay - Sachs | AR |
BRCA1/BRCA2 | Hereditary breast cancer and ovarian I and II | AD |
NextGen recommened to?
To everyone who is planning a pregnancy. Especially:
- In case of hereditary diseases in family history
- In case of consanguine marriage
- To members of specific ethnic groups
- To egg and sperm donors participating in programs
Our clinic will help you to choose a donor of gametes with a known genetic status who has been examined using NextGen21 test
technology and capabilities
- Based on highly efficient NGS sequencing technology
- High analytical characteristics (Sensitivity - 99%, specificity - 99%)
- Allows to determine the status of the studied genes with a high degree of accuracy
- Rules out carrier status of the most frequent and severe hereditary diseases
NextGen21 test significantly reduces the likelihood of hereditary diseases in children. Based on the test result, our geneticist calculates the risks and develops recommendations for each individual family.
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specialists of the fertility clinic
I really appreciate the impeccable and professional treatment I got from the kind and wonderful patient coordinator, Alex and Dr Diana! Both of them were always very hopeful about my case, and they answered very rapidly when I had any questions, which always made me feel comfortable and secure during the whole process. After several failed attempts at other clinics, I got pregnant successfully after the first attempt here!
We would like to express our immense gratitude to the entire team at the NGC clinic for their high level of professionalism and incredible support at every stage of our journey. We were absolutely delighted with the quality of care and the level of service provided.
I had an excellent experience with NGC Clinic. From the initial communication with Dr. Diana and Alex to my arrival at the airport — everything was perfectly organised. Despite arriving at midnight, I was warmly welcomed and taken care of immediately. At the clinic, I never had to wait for an appointment. The atmosphere was calm, private, and very well-structured.
I struggled with infertility for 17 years and went through many attempts to become a mother, including 17 unsuccessful IVF cycles at different clinics in Serbia and the Czech Republic. I never became pregnant, nor did I ever achieve a positive beta result. Eventually, I had given up, as I was already in my forties, which at that time felt too late for me. Then I discovered the Next Generation Clinic (NGC), and I decided to try with them.
After several unsuccessful treatments in Greece and Ukraine (donor sperm, own egg IVF), I came across NGC positive reviews while searching online. I was really desperate as 5 years passed and I was still in the same place. I had my doubts at the beginning (mostly related to the international situation and the military conflict), but I can say now that this was the best that happened to me in the last 10 years.
We had a really great experience with the donor program and got results on the very first try - healthy embryos, and one of them is already our son. All our wishes were taken into account, and we really appreciated the support during the more sensitive parts of choosing a donor. Alexander’s coordination was amazing. The lab is very impressive.
Superb Clinic and great services by all staff. Very friendly approach and professionalism to the smallest details. I am grateful to Dr Diana Lobzeva, who did my treatment for IVF and made me feel comfortable, and was so supportive of us. She speaks perfect English, and she is a doctor, very well trained and great as a Surgeon Gynaecologist as well. I felt no pain at all during the procedure!
We had various medical treatments without any success in our country, so we decided our only option left was to have IVF with an egg donor. To be able to choose the donor by ourselves, based on pictures, in a big European database was very important for us. The staff, receptionists, translators, medical professors were first-class.
I'm writing this review with the most precious gift in my arms, my much longed for baby girl, who was born in March of this year, thanks to the wonderful treatment and care that I received from the team at NGC. For the first time during my years of treatments I felt that I was really being listened to and my concerns being addressed. No stone was left unturned!
When we wanted a sibling for our daughter we turned to NGC in St.-Petersburg. Alex from NGC was very helpful in providing us with information, egg donors, pricing and logistics. He set us up with Dr Valentina Denisova who gave us an hour of her time and explained and advised us on the medical possibilities, requirements and procedures of the NGC via video conference.
I couldn't recommend Next Generation Clinic more! The facilities are state-of-the-art and every member of staff has been polite and professional. The communication (in perfect English, as we unfortunately don't speak Russian) has always been prompt and reliable, thanks to fantastic Alex who has been helpful all along. Dr Valentina Denisova and the embryology team have done an excellent job. I got pregnant following the first embryo transfer, we are grateful!
Firstly I would like to thank Alex and Dr Valentina for the level of care and compassion shown to me throughout our IVF journey. The communication and response time was second to none. Replies within the hour! Dr Valentina was very reassuring when I become anxious or I had any sort of worries/concerns, she always put me at ease answering any questions I may of had.
We are so thankful for everything. This is our 1st IVF, and we are glad it was successful. God bless you all!
We had directly a good feeling when talking to the international manager of NGC who was very helpful, reliable and fast to answer any question we would have. I gave birth in spring 2022 to a healthy baby. This pregnancy and birth happened thanks to NGC, and we are really grateful to them. We would certainly recommend NGC.
We travelled from Ireland to have our IVF treatment in 2022, and I am pleased to say that it was a fantastic experience. The team at NGC clinic provided exceptional care and attention. The doctors and staff were all incredibly knowledgeable and supportive throughout the entire process. I felt comfortable and informed at all times. The facilities and equipment at NGC clinic are top-notch, and I felt confident that I was in good hands.
Best clinic ever, dreams come true here. If you want to achieve the result at your first attempt, this is where you should go. The doctors were absolutely amazing, Ksenia and Alexander were simply the best. Everyone is always willing to help and answer all your questions. The staff controls everything to make your journey smooth and productive.
"All in all, an exceptional experience." After we had experiences with fertility clinics in three different countries in Europe (two of them in the EU), we chose Next Generation Clinic (NGC) in St. Petersburg, Russia. Our choice was initially based on the fact that they offer a large database of donors. Donors are often already genetically screened, and the process of getting the biological material is significantly easier than in other places.
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