Chances of Miscarriage with IVF: Understanding the Risks and Realities
Statistics claim that 18-30% of IVF cycles end in miscarriage. Patients seeking fertility clinics should not give up. A detailed study of the problem helps to reduce the chance of miscarriage, increasing the pregnancy rate and successful delivery rate.
Important. The NGC Clinic offers IVF treatment performed by experienced specialists. We will help to identify chromosomal abnormalities. Preliminary genetic diagnostics will reduce the risk of miscarriage.

Understanding miscarriage in IVF pregnancies
The practice of leading reproductive centers shows that approximately 80% of miscarriages occur in the first trimester. Therefore, if after IVF the patient has crossed 12 weeks of pregnancy, and the fetus is developing normally, the risk of miscarriage decreases. When planning to undergo treatment for infertility, you should understand that embryo transfer is a complex procedure. To minimize the risk of miscarriage, choose clinics with an impeccable reputation and a large number of positive reviews. The NGC Reproductive Center will help to cope with fertility problems even if the mother's age is close to critical for in vitro fertilization.

Definition of miscarriage
In case of spontaneous termination of pregnancy before 22 weeks, the doctor diagnoses a miscarriage. In order for assisted reproductive technologies to give a positive outcome and result in the birth of a healthy child, it is necessary to strictly follow all the recommendations of the reproductive doctor. Tell the specialist about your problems in as much detail as possible during the consultation. The more complete your medical history, the easier it is for the specialist to determine the causes of infertility and choose effective treatment.
How IVF affects the frequency of miscarriages
The primary cause of miscarriage during IVF is not the procedure itself. In most cases, the increased risk of miscarriage is due to the reasons for the development of infertility. The presence of endocrine pathologies, advanced maternal age, frequent abortions in youth, the presence of chronic pelvic diseases and other reasons become a risk factor for miscarriage during IVF procedure. Preliminary therapy before IVF inhibits all chronic diseases. However, stable remission ends after embryo implantation and chronic ailments worsen.
The immune system, working under stress, loses its effectiveness. The amount of hormones produced by the body that ensure the normal course of pregnancy will drop sharply. Each stage of pregnancy during IVF has its own risks. Therefore, the reproductive specialist who performed fertilization passes the patient to their local ObGyn specialist to ensure that the patient remains monitored throughout the pregnancy. In case of any deviations, the appearance of unpleasant symptoms, you should immediately contact a doctor and strictly follow all the specialist's instructions.
Note. What you read on the Internet cannot be the basis for treating infertility. Only experienced specialists, having a detailed anamnesis in hand, are able to choose the right path to treating low fertility. Consult the NGC clinic and fight infertility under the guidance of experienced doctors.
Comparison of miscarriage rates: Undergoing IVF vs. natural conception
The miscarriage rate in IVF and natural conception is approximately the same. An embryo transferred into a healthy young body will develop normally, and the pregnancy will proceed without complications. However, people suffering from infertility go to reproductive centers because they cannot conceive a child naturally. Therefore, you need to understand the reasons, consult a doctor and remember a few simple truths.
- Understand the causes of early pregnancy miscarriages.
- Do not take any radical measures immediately after a miscarriage. Let the body recover.
- If you first notice blood on your underwear, do not panic. See a doctor immediately.
- If you experience aching pain in the lower abdomen, contact your doctor and go to hospital for preservation if he recommends.
- After a miscarriage, you will need emotional support. The help of a psychologist, relatives, friends will help you overcome a difficult period.
The main thing in case of miscarriage is not to get depressed. It does not matter after IVF treatment or natural pregnancy, there is a high risk of losing the embryo if there are genetic diseases that reduce the chances of normal development of the embryo. It is necessary to undergo a detailed examination in advance, take tests and analyzes. The success rates of IVF directly depends on the preliminary preparation and experience of the staff of the reproductive center.

Statistical review
The first three months after IVF are the most stressful, since during this period a miscarriage can most often occur.
- Fifth week. The main risk factors of this period are the presence of problems with implantation or chromosomal abnormalities.
- Sixth week. Most often, the root cause is abnormal embryonic development or errors during implantation.
- Seventh week. The risks of miscarriage are lower, but they exist. The main reasons can be health problems in the mother or poor quality of the transplanted embryo.
- Eighth week. There is a much higher chance of carrying a healthy child. The main factors of miscarriage can be the age and health of the expectant mother, as well as the quality of the implanted embryo.
Remember. By contacting the NGC reproductive center, the likelihood of miscarriage is significantly reduced. High-quality embryos, professionally performed fertilization after a detailed medical history increases the chances of a successful birth of a baby.

Interpretation of numbers
There is no need to be afraid of treatment by means of assisted reproductive technology. The procedure has long become commonplace and reproductive specialists have already managed to help many couples suffering from childlessness. Out of 100 women after IVF, up to 20% experience miscarriages. Moreover, 80% of them experience this misfortune during the first trimester. The most dangerous period for miscarriage, according to statistics, is 12 weeks. Understanding the reasons and the time when the danger is greatest makes it easier to overcome this problem.
Factors affecting the risk of miscarriage during IVF
Numerous studies have not identified direct reasons for the influence of IVF on miscarriage statistics. People who cannot conceive a baby naturally due to genetic diagnosis, chronic diseases or other reasons come to the reproductive center. Therefore, the risk of miscarriage is high. You should remember this and help doctors solve the problem. Strict adherence to the recommendations of the reproductive doctor will reduce the risk of miscarriage.
Age of the mother
The main contingent of patients in reproductive clinics are women over 35 years old. At the age of 35-45, the risk of miscarriage is 20-35%. If the age is over 45, the risk of miscarriage is 50%.
Quality of the embryo
Low quality of the embryo is certainly a risk factor for miscarriage. The NGC clinic uses only proven, high-quality donor material. Therefore, this reason is immediately removed. Only the health problems of the expectant mother remain, which reduces the risk of miscarriage.


Genetic factors
Before IVF, it is necessary to undergo a full laboratory and machine examination. This will help to identify thyroid dysfunction, hyperprolactinemia, high levels of male hormones, improper ovarian function, and other factors that can cause a miscarriage.
Uterine factors
During the consultation, you need to truthfully tell the doctor how many times you have had an abortion or otherwise terminated a pregnancy. Congenital defects begin to increase sharply with the production of hormones during pregnancy, which causes a miscarriage.
Lifestyle and environmental factors
The successful bearing and birth of a child largely depends on lifestyle and the environment. There are several factors that can cause a miscarriage at an early or late stage. Knowing about them makes it easier to prevent such a danger.
Excessive physical activity. Intensive training, running, extreme tourism, and other reasons can lead to a miscarriage.
- Stress, depression, psychological pressure, scandals in the family or at work.
- Smoking, drug use or alcohol.
- Eating high-calorie, fatty or GMO foods.
- Stressful work schedule without rest or days off.
- Bruises to the abdomen, head or reproductive organs.
Please note. Before and after IVF, a woman should radically change her lifestyle. Pay more attention to the quality of nutrition. Completely stop intense training and focus on walks in the park. No tobacco, alcohol or drugs.
The IVF process and its impact on the risk of miscarriage
By contacting the NGC reproductive center, where highly professional specialists use the latest methods of artificial insemination, the risks of miscarriage are reduced as much as possible. All procedures are performed by experienced reproductive specialists after collecting a detailed anamnesis and conducting special therapy.
Ovarian stimulation
With hyperstimulation of the ovaries, they increase sharply. Fluid can accumulate in the abdominal cavity, near the lungs, which causes attacks of suffocation. In such a situation, pregnancy after an IVF cycle often ends in miscarriage at an early stage.

Embryo cultivation and selection
After the puncture and collection of follicular fluid, the samples are sent to the laboratory. The quality and viability of the eggs are examined. If necessary, the ICSI procedure is performed. The fertilized eggs will remain under observation for the following 7 days. An embryo that successfully reaches the blastocyst stage can be transferred in the uterus or cryopreserved.

Embryo transfer methods
The embryo is transferred using a special, sterile, thin catheter. The procedure is painless and does not require anesthesia. If there is a deformation of the uterine canal, this may cause minor discomfort. If during the transfer the embryo is implanted in the fallopian tube, an ectopic pregnancy occurs. In this case, surgical intervention will be required. Simultaneous attachment to the uterine cavity and fallopian tube or the development of inflammation is possible. Any side effects from IVF are possible only if you use the services of questionable clinics. The NGC Reproductive Center guarantees excellent quality of service. The staff regularly undergoes internships to improve their professional skills. Accidents are completely excluded here.
It is worth mentioning that double (and triple) embryo transfers decrease the chances of carrying the pregnancy to full term. If several embryos successfully implant, a patient with even a slightly burdened gynecological history exposes herself and her pregnancy to unnecessary higher risk.
Miscarriage Prevention Strategies during IVF
Minimizing risks during IVF requires regular monitoring by a gynecologist. The more the reproductive doctor knows about your health problems, the easier it is for him to choose a treatment method. At the same time, parents should also work on themselves.
- Completely get rid of bad habits.
- Try to reduce stress factors.
- Eat right, without spicy, fatty and GMO foods.
- If you work in a hazardous industry, you need to quit.
- Extra pounds are a serious factor in early miscarriage.
Share your joys with your relatives. They will always support you in difficult times.
Genetic testing before implantation
People's chromosome sets determine their life potential from the moment of conception. Since up to 60% of miscarriages are caused by genetic abnormalities, a genetic test is very important during IVF. Conducting PGT increases the chances of a normal pregnancy after artificial insemination.
Optimization of the uterine environment
Uterine health during IVF is an important part of the procedure. A thorough examination is required to identify and eliminate all changes in the uterus. For successful implantation of the embryo, the uterine mucosa must be in perfect condition and have the required thickness. Be sure to conduct a uterine susceptibility test before IVF. After IVF, eat right and strictly follow all the instructions of the reproductive specialist.

Hormonal support
Each woman after IVF is prescribed a course of hormonal support. This reduces the risk of miscarriage in the early stages. Patients are prescribed progesterone, which changes the structure of the endometrium, helping the embryo to attach to the uterus. Contractile abilities of the uterus decrease, the cervical canal is sealed. This significantly reduces the risk of miscarriage. Estrogens can support a woman after IVF for up to 8 weeks. The duration of support, dosage is determined by the reproductive specialist. The more accurately the patient follows the specialist's recommendations, the lower the likelihood of miscarriage.

Emotional aspects of miscarriage during IVF
Infertility itself is a serious test for any woman. Miscarriage after IVF can lead to serious psychological problems. The main thing is not to withdraw into yourself so that depression does not lead to mental disorders. Remember that several IVF cycles may be needed until the long-awaited baby is born.
How to cope with loss
Many people have a very hard time with miscarriage. A few simple tips will help you cope with the trouble:
- Let the grief come out, do not withdraw into yourself;
- Support from family, friends and colleagues at work will help you overcome the pain;
- Find a support group online for those facing a similar problem;
- Pay attention to yourself, buy new clothes, change your hairstyle, find a hobby;
- Advice from an experienced psychologist will help you overcome a difficult period faster.
Support Systems and Resources
After a miscarriage, many women immediately begin planning a new IVF cycle. Don't rush.
- Give your body time to fully recover and prepare for new challenges.
- Make sure that negative emotions are in the past and you can enjoy life again.
- Before a new IVF cycle, be sure to undergo a full examination.
- Consult a reproductive doctor.
Careful preparation will help you cope with low fertility, get pregnant and give birth to a baby. There are many special resources on the Internet that help women who are faced with the problems of miscarriages after IVF.
Advances in IVF technology that reduce the risk of miscarriage
To minimize the risk of miscarriage, conduct PGT. Timely detection of genetic and embryonic pathologies makes it easier for the doctor to choose a treatment method. Today, PGT is the most proven and accurate methodology for identifying genetic diseases. The test increases the chances of success with IVF and minimizes the risk of miscarriage.
Frame-by-frame embryo monitoring
NGC uses embryo incubators equipped with Time-Lapse technology. Its application helps embryologists assess each embryo and make precise forecasts on its use.
- Embryologists track the development and condition of each individual embryo in real time.
- There is no need to extract the embryos from the incubator for assessment. Hence, the embryos do not experience stress.
- Frame-by-frame recording and AI assistance make it possible to effectively determine the best embryo with optimal parameters for transfer procedure.
- Patients can receive a video showing the growth of their embryos for personal use.
In the future, parents can receive a video of their embryo growing before IVF.


When to Consider Additional Testing
Additional tests can significantly reduce the risk of miscarriage, so for women over 35-45 years old, this is a mandatory procedure. An accurate assessment of fertility using tests allows the reproductive specialist to choose the optimal IVF program for a particular couple.
Repeated pregnancy loss during IVF
After recurrent miscarriage, both partners must be tested before a new IVF cycle. This will help determine the causes of the miscarriage and conduct a new cycle successfully. The more data the reproductive specialist receives, the easier it is for him to prescribe treatment and choose the path to success.
Diagnostic capabilities
An effective infertility treatment strategy is possible only with the most accurate data on patients.
Female testing includes several points
- Hormonal testing of ovarian reserves and oocyte quality. Hormones tested:
- follicle-stimulating;
- luteinizing;
- thyrotropic;
- anti-Müllerian;
- estradiol.
Ideally, the test is performed on the 2nd-3rd day of the cycle.
2. Basic ultrasound of the reproductive organs.


Conclusion
The IVF cycle is a difficult path that must be taken with a clear understanding of all the possible risks. If a miscarriage occurs, there is no need to panic. Enlist the support of friends, relatives, acquaintances, psychologists to get through this difficult period. Do not despair and try again. At the NGC clinic, they will help you cope with the difficult task of getting pregnant, carrying and giving birth to a healthy baby.
Our team stood at the origins of reproductive medicine in Russia and is known all over the world as the highest-level professionals.
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FAQs
The IVF procedure itself does not increase the risk of miscarriage. The problem is that people with fertility problems and reproductive organ function seek help from reproductive centers. Therefore, the risk of miscarriage in the early stages increases.
The first trimester is the most dangerous. Most often, miscarriages occur in the first 6-12 weeks. Then the risk of miscarriage decreases but does not disappear completely.
The older the woman, the higher the risk of miscarriage. At the age of 35-45, the risk of miscarriage is 25-35%. Over 45, it increases to 50%.
One of the significant factors in the occurrence of miscarriage is an unhealthy lifestyle. Quit smoking, drinking alcohol or taking drugs. Eat right to normalize your weight and the risk of miscarriage will be significantly reduced.
The main thing is not to panic. Consult with your doctor about how to recover quickly to start a new IVF cycle.