Common questions about IVF: is in vitro fertilization painful?
In vitro fertilization (IVF), or "test tube baby" is an assisted reproductive technology that has long been a part of our lives. The technique is used to treat infertility. In English, this procedure is abbreviated as IVF. The first successful IVF process was carried out in the UK in 1977, which led to the birth of Louise Joy Brown, the first person conceived "in a test tube". In the Soviet Union, the first child conceived with the help of IVF was born in February 1986.
Please note. Pregnancy achieved with the help of in vitro fertilization (IVF) is no different from natural pregnancy and is not accompanied by specific complications.


A detailed overview of the IVF procedure: stages and nuances
In vitro fertilization (IVF) begins with mature eggs being removed from women using a fine needle under ultrasound control and fertilized with sperm in a laboratory. The process only seems simple. In addition to blood tests and infection tests, the woman undergoes a series of specialized examinations and consultations. These include a Pap smear, an ECG, a mammologist examination, and, if necessary, a mammogram.
Beginning of treatment: preparation and prevention of discomfort
Before the start of the procedure, the reproductive specialist, if necessary, prescribes birth control pills (or other hormonal pills) or estrogen to the woman. These drugs help prevent the formation of cysts on the ovaries and regulate the menstrual cycle. Some women experience side effects such as mild bloating, cramping or swelling of the ovaries, these sensations do not cause discomfort during IVF and rarely cause pain
Ovarian stimulation: the next stage of IVF preparation
Synthetic hormones are used to stimulate the ovaries so that they produce multiple eggs. The hormones are administered through subcutaneous injections that the woman gives herself.
Egg retrieval procedure
During egg retrieval, the woman is sedated, which eliminates pain. After the procedure, cramping similar to menstrual cramps may occur, but they are short-lived.
Sperm collection and preparation
The woman's partner involved in the IVF process provides a sperm sample, or donor material is used.


Fertilization in the laboratory: two methods
After the eggs have been assessed for maturity and quality, sperm are injected into the egg using intracytoplasmic sperm injection (ICSI) or IVF insemination, where concentrated spermis mixed with each egg.
Embryo Transfer and Freezing
The embryo develops over five to six days. When the embryos are ready, one embryo is transferred vaginally into the woman’s or surrogate’s uterus using a catheter. The remaining blastocysts are frozen for later use. The medical procedure of embryo transfer causes minimal discomfort and does not require sedation.
Fresh vs. Frozen Embryos: Risks and Benefits
Fresh embryo transfers have risks and discomfort associated with the synchronization of the donor and recipient cycles and the possibility of development (OHSS). Frozen embryo transfers improve timing and reduce the risks associated with the procedure.
The final step: pregnancy test
10-14 days after the fertilization procedure, a pregnancy test is performed to determine the success of the procedure.
IVF treatment is a gradual and complex process that allows you to become pregnant despite the difficulties and risks associated with it.
Note. Nowadays, successful IVF has reached such a level of perfection that the need to transfer several embryos at once has disappeared. It is worth considering that even one transferred embryo can split.
What are the painful procedures during IVF?
Despite the fact that the procedure does not cause discomfort, sometimes IVF is painful.
- Ovulation stimulation is aimed at the maturation of several eggs with the help of hormonal drugs. As a result, one or both ovaries increase in size, which leads to discomfort and abdominal pain.
- First, anesthesia is administered, then the procedure for collecting eggs is performed under ultrasound control. During the procedure, the doctor punctures the wall of the vagina and ovary, which contributes to microtrauma. Pain after puncture in the lower abdomen is normal, which goes away after 3-5 days. A reproductive specialist will tell you about possible lifestyle restrictions after the puncture.
- The process of extracting eggs and implanting the embryo is accompanied by minor discomfort in the lower abdomen or lower back. If the pain becomes severe, contact your doctor immediately.
IVF injections may cause common side effects for some women. These are short-lived and manageable.
- Bruising or discomfort at the injection site.
- Mood changes.
- Changes in appetite.
- Fatigue.
- Headaches.
- Hot flashes.
- Nausea.
- Bloating.
- Breast tenderness.
- Cramping.
- Decreased libido.
- Menstrual bleeding or spotting.
Rarely, ovarian hyperstimulation syndrome (OHSS) may develop, which is caused by excessive follicle growth and fluid leaking into the abdominal cavity. Symptoms of OHSS include abdominal bloating, nausea, and weight gain. In mild cases, rest and hydration are sufficient; in severe cases, hospitalization is necessary.
Interesting to know. There is a common misconception in society that “test tube babies” are inferior and developmentally delayed. But numerous studies indicate the opposite. A strong and viable embryo is selected for IVF.


Pain treatment options
In case of severe pain, malaise and deterioration of health, consult a doctor. Even if the alarm turns out to be false, a consultation with a reproductive specialist will not be superfluous. Doctors offer recommendations to help relieve discomfort and improve the condition.
Nutrition
During IVF, it is important to carefully choose foods and maintain a balanced diet. Often, abdominal pain can be caused by food products. Pay attention to protein products, reduce carbohydrates. Include lean meat, cheese, fish, dairy products, fruits and vegetables in your diet. Avoid spicy, smoked, fried foods, sweets and fast food.
Water regime
To avoid dehydration, drink enough clean water every day.
Rest
Try to rest more. Learn to relax and not give in to anxiety. Calm music, meditation, favorite films and TV series or breathing practices will help.
Medicines
Take the drugs in the protocol only after consulting a doctor. If you are afraid of severe pain, check the permissible drugs and their dosage in advance.
Remember. Drugs for the treatment of infertility can cause hormonal changes or side effects.
Tips for reducing discomfort
After IVF, it is important to reduce physical activity: avoid not only sports, but also household chores. Try not to make sudden movements or bend over. Rest and lie down, even if you do not feel pain. A light walk in the fresh air will be useful if you feel well.
Adequate sleep plays a role in recovery after IVF. Sleep at least eight hours, preferably at night. Go to bed before ten in the evening.
Manage stress before and after IVF. Mild sedatives based on valerian and motherwort are suitable for relieving tension. Take other medications only as prescribed by a doctor. Often, the support of loved ones or a consultation with a psychologist helps.
It is recommended to abstain from sexual intercourse after IVF for five days. During this period, remain completely calm so that the uterus does not contract. This interferes with the implantation of the embryo. As soon as the ultrasound confirms successful implantation and the safety of the fetus, it is time to return to the usual rhythm of life.


Coping with emotional and physical issues
The process of fertilization is not easy, and IVF injections are painful. It is important to maintain hope, it is important to remain realistic. It often takes at least three attempts at IVF with your own eggs to successfully conceive, while donor eggs provide results on the first try. Even so, failures are emotionally difficult. Don’t be afraid to experience the feelings that may arise.
It is natural to feel upset after an unsuccessful IVF procedure. Take time for yourself, practice self-compassion, and remember that you are not alone. Many couples struggling with infertility face similar difficulties. Depression after IVF is common. Failures make it difficult to remain optimistic.
Hormonal changes associated with IVF can cause depression and anxiety. In such cases, the help of a therapist or fertility consultant is useful in managing emotions. Women’s experience has shown that support from interest groups and talking to others who are going through similar experiences also helps.
Important. The IVF procedure does not affect the ovarian reserve in any way.
NGC Clinic: Infertility is not the final sentence
NGC Clinic is a medical center specializing in the treatment and medication of infertility using assisted reproductive technologies (ART). The clinic is equipped with the latest technical means and offers unique methods of infertility treatment thanks to experienced specialists in the field of reproductive medicine and embryology.
- IVF efficiency is more than 50%.
- Experience - more than 20 years.
The staff is proud of the largest egg and sperm donor bank in Russia.


Treatment methods
In modern reproductive healthcare, there is a wide range of infertility treatment methods, each of which has unique features and advantages. The main approaches include both time-tested assisted reproductive technologies and innovative methods.
IVF (In Vitro Fertilization) |
The oldest method of treating infertility, it involves ovarian stimulation, egg retrieval, fertilization and embryo transfer into the uterus. |
ICSI (Intracytoplasmic sperm injection) |
The sperm is injected directly into the egg using modern technology. This increases the chances of fertilization. |
PGT-A (Preimplantation Genetic Testing) |
Embryo analysis to detect genetic abnormalities and selection of healthy blastocysts for transfer. |
Vitrification and cryopreservation |
Long-term storage of embryos, oocytes and sperm in low-temperature conditions with high survival rate after thawing. |
TESA, TESE, PESA, MESA |
Methods of obtaining spermatozoa in severe andrological disorders. |
Egg and sperm donation |
Large selection of donors with detailed profiles. Genetic pre-testing. Participation in Open ID programs. |
Embryo adoption |
300+ embryos available for adoption. Genetically tested, double donation possible. |
Want to learn more about advanced IVF methods and get support at every stage of your journey to parenthood? Contact NGC Clinic! Qualified experts will help you find an individual solution and achieve the desired result. Sign up for a consultation or fill out the online form for a free consultation today and take the first step towards making your dream family come true.
Summary
In vitro fertilization is painful and is a complex, but highly effective method that increases fertility. Although the egg retrieval procedure sometimes causes some discomfort, most stages are painless and without complications. An important aspect is proper preparation and following the doctor's recommendations, which helps to minimize possible discomfort. Modern methods and technologies of NGC Clinic have made IVF injections accessible and safe, and also provided high chances of successful conception. When caring for infertility, do not forget to seek medical help if you have doubts or painful symptoms to ensure the expected result and well-being.

Our team stood at the origins of reproductive medicine in Russia and is known all over the world as the highest-level professionals.
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FAQs
Cramping, lower abdominal pain similar to menstrual cramps.
The pain usually lasts for 3-5 days.
Yes. Drink plenty of water.
They can mask the symptoms of possible complications, delaying the necessary medical care.
Yes, the best person to discuss them with is the fertility specialist who is performing the procedure.